In order to search for effective anti-radiation drugs, we synthesized tetrahydrothiazole compounds, in which 2, 2-dimethyltetrahydrothiazole hydrochloride (2, 2-dimethyltetrahydrothiazole hydrochloride) 2-Dimethylthiazolidine hydrochloride (DM TD) has a significant protective effect against ionizing radiation damage in mice and against 60Co γ-ray 3.25 Gy in a single whole-body irradiation in dogs, either intravenously or intramusculally Or oral or skin smear has a better protective effect [2]. The drug is used in tumor radiotherapy patients, and has a certain effect on reducing radiotherapy response, but the drug has disadvantages such as odor, moisture absorption and so on. In order to overcome the above shortcomings, we synthesized its organic acid salts.