Factory supply tadalafil CAS 171596-29-5 with good quality

24-11-2023
Tadalafil is a PDE5 inhibitor marketed in pill form for treating erectile dysfunction (ED) under the name Cialis, and under the name Adcirca for the treatment of pulmonary arterial hypertension. In October 2011 the U.S. Food and Drug Administration (FDA) approved Cialis for treating the signs and symptoms of benign prostatic hyperplasia (BPH) as well as a combination of BPH and erectile dysfunction (ED) when the conditions coincide. It initially was developed by the biotechnology company ICOS, and then again developed and marketed world-wide by Lilly ICOS, LLC, the joint venture of ICOS Corporation and Eli Lilly and Company. Cialis tablets, in 2.5mg, 5mg, 10mg, and 20mg doses, are yellow, film-coated, and almond-shaped. The approved dose for pulmonary arterial hypertension is 40mg (two 20-mg tablets) once daily.
Tadalafil is also manufactured and sold under the name of Tadacip by the Indian pharmaceutical company Cipla in doses of 10mg and 20mg.
On November 21, 2003 the FDA approved tadalafil (as Cialis) for sale in the United States as the third ED prescription drug pill (after sildenafil citrate (Viagra) and vardenafil Hydrochloride (Levitra)). Like sildenafil and vardenafil, tadalafil is recommended as an 'as needed' medication. Cialis is the only one of the three that is also offered as a once-daily medication.
Moreover, tadalafil was approved in May 2009 in the United States for the treatment of pulmonary arterial hypertension and is under regulatory review in other regions for this condition. In late November 2008, Eli Lilly sold the exclusive rights to commercialize tadalafil for pulmonary arterial hypertension in the United States to United Therapeutics for an upfront payment of $150 million.

Basic Info

Chemical Name

Tildenafil

use


Pharmaceutical intermediate

CAS No.

171596-29-5

Molecular Formula

C22H19N3O4

Molecular Weight

389.40400

PSA

74.87000

LogP

2.08710

Numbering system

MDL numberMFCD07771966

Properties

Appearance & Physical State

Off-White Cyrstalline Solid

Density

1.51 g/cm3

Boiling Point

679.1ºC at 760 mmHg

Melting Point

298-300ºC

Flash Point

364.5ºC

Refractive Index

1.705

Vapor Pressure

5.29E-13mmHg at 25°C

N-Carbethoxy-4-piperidone

lead diacetate trihydrate

6080-56-4

N-Carbethoxy-4-piperidone

lead diacetate trihydrate

6080-56-4

N-Carbethoxy-4-piperidone



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