Veterinary drug API Diclazuril cas 101831-37-2
101831-37-2 - Names and Identifiers
| Name | Diclazuril |
| Synonyms | Nuoqiu Vecoxan CLINACOX DICLAZURIL Diclazuril DICLAZUTIL |
| CAS | 101831-37-2 |
| EINECS | 1806241-263-5 |
| InChI | InChI=1/C17H9Cl3N4O2/c18-10-3-1-9(2-4-10)12(7-21)16-13(19)5-11(6-14(16)20)24-17(26)23-15(25)8-22-24/h1-6,8,12H,(H,23,25,26) |
| InChIKey | ZSZFUDFOPOMEET-UHFFFAOYSA-N |
101831-37-2 - Physico-chemical Properties
| Molecular Formula | C17H9Cl3N4O2 |
| Molar Mass | 407.64 |
| Density | 1.56±0.1 g/cm3(Predicted) |
| Melting Point | 290.5° |
| Appearance | Pale yellow or white powder |
| Color | White to Light yellow to Light orange |
| Merck | 14,3080 |
| pKa | 5.89±0.20(Predicted) |
| Physical and Chemical Properties | Pale yellow or off-white powder, practically insoluble in water, slightly soluble in ethanol, ether, soluble in N,N-2 methyl Formamide (DMF), dimethyl sulphone (DMSO), tetrahydrofuran (THF). Melting Point: 291-297 ℃ |
| Use | Anti-coccidial drugs, have a control effect on a variety of coccidia |
uses and characteristics
dicezuril is a triazine phenylacetonitrile compound. it is a new type, high-efficiency (only 1 g of the compound is added per ton of feed), low toxicity (no poisoning phenomenon is found in 50 times excess) anticoccidiosis, and is widely used in chicken coccidiosis. In addition, it has preventive and therapeutic effects on a variety of coccidia, and can also be used to prevent ducks, quails, turkeys, geese and rabbits from getting coccidiosis. Dikzhuli is a brand-new synthetic non-ionic portable anticoccidial drug. The anticoccidial index of the six main species of Eimeria in chickens is above 180, which is a high-efficiency anticoccidial drug. It also has the characteristics of low toxicity, broad spectrum, small dosage, wide safety range, no drug withdrawal period, no toxic side effects, no cross-resistance, and no influence of the feed granulation process. This product can be added to the feed for a long time without stopping the drug before slaughter. (does not affect broiler exports); does not affect the growth and development of livestock and poultry.
Dikezuli has excellent effects on chicken tenderness, pile type, poison, Brucell, and giant Eimeria. After medication, it can effectively control the occurrence and death of cecal coccidia, and even make The oocysts of diseased chickens disappear. It has good effect on duck coccidia and rabbit coccidia. Clinical trials have shown that the control effect of Diquanil on coccidia is better than other conventionally used anticoccidial drugs and monensin plasma carrier anticoccidial drugs; for fluoropurine (Arprinocid), chloropyridine, and Changshannone, Oxyphenanidine, Monensin-resistant Eimeria tenella, the application of Diquanil is still effective. For example, the concentration of 1 mg/kg feed can effectively control duck coccidiosis, and its effect even exceeds that of polyether antibiotics. 1mg/kg of medicine was fed to rabbits, which was highly effective against liver coccidia and enterococcus in rabbits. Its disadvantage is that long-term medication will appear drug resistance, so it should be used in shuttle or short-term use or alternate with other anticoccidial drugs.
