Product Description

  MK677 CAS 159752-10-0 is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue, mimicking the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. MK677 has been demonstrated to increase the release of, and produces sustained increases in plasma levels of several hormones including GH and insulin-like growth factor 1 (IGF-1), but without affecting cortisol levels.  MK677 CAS 159752-10-0 is currently under development as a potential treatment for reduced levels of these hormones, such as in children or elderly adults with growth hormone deficiency, and human studies have shown  MK677 CAS 159752-10-0 to increase both muscle mass and bone mineral density, making it a promising therapy for the treatment of frailty in the elderly. MK677 CAS 159752-10-0 also alters metabolism of body fat and so may have application in the treatment of obesity.

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